BDBM50379830 CHEMBL2011700

SMILES OC(=O)c1ccc(CN2C(=O)\C(S\C2=N/c2ccc(cc2)C(F)(F)F)=C\c2cccc(OCc3ccccc3)c2)cc1

InChI Key InChIKey=HLJVHKMEFSMMFG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50379830   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50379830(CHEMBL2011700)
Affinity DataIC50: 5.60E+3nMAssay Description:Competitive inhibition of GST-tagged human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Line-Weav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50379830(CHEMBL2011700)
Affinity DataIC50: 1.20E+4nMAssay Description:Competitive inhibition of GST-tagged human recombinant LMW-PTP IF1 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Lin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50379830(CHEMBL2011700)
Affinity DataIC50: 1.00E+5nMAssay Description:Competitive inhibition of human recombinant TCPTP using p-nitrophenylphosphate as substrate by Line-Weaver Burk plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50379830(CHEMBL2011700)
Affinity DataIC50: 1.50E+5nMAssay Description:Competitive inhibition of GST-tagged human recombinant LMW-PTP IF2 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate by Lin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed