BDBM50380076 CHEMBL2012905

SMILES OC[C@@H](O)CONC(=O)c1c2CCCn2c(=O)c(F)c1Nc1ccc(I)cc1F

InChI Key InChIKey=RTFKPEGPVPIODZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50380076   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Takeda California

Curated by ChEMBL

LigandBDBM50380076(CHEMBL2012905)Copy SMILESCopy InChI

Affinity DataIC50: 39nMAssay Description:Inhibition of MEK1-mediated ERK1 phosphorylation using IPTTPITTYFFFK-5FAM-COOH as substrate by fluorescent polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL