BDBM50381094 CHEMBL2017553

SMILES CCC(O)(CC)c1ccc2cc([nH]c2c1)-c1n[nH]c2ccsc12

InChI Key InChIKey=OHAIFZDRLDEOAC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50381094   

TargetTyrosine-protein kinase ITK/TSK(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381094(CHEMBL2017553)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Itk (357-620) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation coun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381094(CHEMBL2017553)
Affinity DataIC50: 66.5nMAssay Description:Inhibition of Txk autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381094(CHEMBL2017553)
Affinity DataIC50: 186nMAssay Description:Inhibition of recombinant N-terminus His6 tagged Syk (343 to 635) autophosphorylation expressed in insect Sf9 cells using [33P]ATP by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Sanofi Us

Curated by ChEMBL
LigandPNGBDBM50381094(CHEMBL2017553)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Lck autophosphorylation using [33P]ATP by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed