BDBM50381371 CHEMBL2016721

SMILES CC(C)NC(=O)C1CCN(CC1)c1nc(C)c2cc(NC(=O)COc3ccc(Cl)cc3)ccc2n1

InChI Key InChIKey=PUKCRVYBPKTZCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381371   

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381371(CHEMBL2016721)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by SPA binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381371(CHEMBL2016721)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH peptide mediated response measuring [3H]inositol phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed