BDBM50381741 CHEMBL2023242

SMILES Cn1c(OCC(=O)[C@@]2(O)CC[C@H]3[C@@H]4CCC5=Cc6c(C[C@]5(C)[C@H]4[C@@H](O)C[C@]23C)cnn6-c2ccc(F)cc2)nc2ccccc12

InChI Key InChIKey=HFZJSXYMSSCKGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381741   

TargetGlucocorticoid receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50381741(CHEMBL2023242)
Affinity DataIC50: 2.90nMAssay Description:Transrepression activity at glucocorticoid receptor in human H292 cells assessed as inhibition of TNF-induced IL8 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50381741(CHEMBL2023242)
Affinity DataIC50: 78nMAssay Description:Transactivation activity at glucocorticoid receptor in rat H4II-E cells assessed as induction of tyrosine aminotransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed