BDBM50382673 CHEMBL2024003

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1CCN(C1)C(=O)P(O)(O)=O

InChI Key InChIKey=IDQDEDVGZLDZLH-UHFFFAOYSA-N

Data  14 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50382673   

TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  16nMAssay Description:Competitive inhibition of PNP in human Jurkat cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  20nMAssay Description:Competitive inhibition of PNP in human PBMC using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  25nMAssay Description:Competitive inhibition of human recombinant PNP using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  30nMAssay Description:Competitive inhibition of PNP in human MINO cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  38nMAssay Description:Competitive inhibition of PNP in human SU-DHL-1 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  50nMAssay Description:Competitive inhibition of PNP in human MC116 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  50nMAssay Description:Competitive inhibition of PNP in human RPMI8226 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  50nMAssay Description:Competitive inhibition of PNP in human DoHH2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  60nMAssay Description:Competitive inhibition of PNP in human K562 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  60nMAssay Description:Competitive inhibition of PNP in human AML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  77nMAssay Description:Competitive inhibition of PNP in human CML cells obtained from patients using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  78nMAssay Description:Competitive inhibition of PNP in human OPM2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  98nMAssay Description:Competitive inhibition of PNP in human HBL2 cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPurine nucleoside phosphorylase(Human)
Academy of Sciences of The Czech Republic

Curated by ChEMBL
LigandPNGBDBM50382673(CHEMBL2024003)
Affinity DataKi:  100nMAssay Description:Competitive inhibition of PNP in human HBL2 tumor cells using MSEG as substrate by Dixon-plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed