BDBM50382724 CHEMBL2023730

SMILES [O-]C(=O)[C@@H]1CCCN1C([S-])=S

InChI Key InChIKey=KXPSZHIUQPHVGH-UHFFFAOYSA-L

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50382724   

TargetCarbonic anhydrase(Fruit fly)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50382724(CHEMBL2023730)
Affinity DataKi:  1.40nMAssay Description:Inhibition of Drosophila melanogaster recombinant carbonic anhydrase-1 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins by CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50382724(CHEMBL2023730)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human CA1 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50382724(CHEMBL2023730)
Affinity DataKi:  4nMAssay Description:Inhibition of human CA12 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50382724(CHEMBL2023730)
Affinity DataKi:  4.10nMAssay Description:Inhibition of human CA9 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLD26647p(Fruit fly)
University of Tampere and Tampere University Hospital

Curated by ChEMBL
LigandPNGBDBM50382724(CHEMBL2023730)
Affinity DataKi:  14nMAssay Description:Inhibition of Drosophila melanogaster recombinant carbonic anhydrase-2 expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins by CO2 hydra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50382724(CHEMBL2023730)
Affinity DataKi:  17nMAssay Description:Inhibition of human CA2 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed