BDBM50382798 [18F]FLUORORASAGILINE

SMILES F[C@H]1Cc2ccccc2[C@@H]1NCC#C

InChI Key InChIKey=NYDFHNRLRLOAGB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50382798   

TargetAmine oxidase [flavin-containing] B(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50382798([18F]FLUORORASAGILINE)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant MAO-B expressed in insect cells assessed as kynuramine hydrobromide oxidation after 20 mins by spectrophotometric ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50382798([18F]FLUORORASAGILINE)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in insect cells assessed as kynuramine hydrobromide oxidation after 20 mins by spectrophotometric ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50382798([18F]FLUORORASAGILINE)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant human MAO-B expressed in insect cells using kynuramine as substrate assessed as formation of 4-hydroxyquinoline measured ev...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed