BDBM50383093 CHEMBL2031576

SMILES Fc1ccc(cc1)-c1ccc(cc1)C(=O)Nc1ccc2cc(CN3CCCC3)cnc2c1

InChI Key InChIKey=KLPGSSBKQHEWRL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50383093   

TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50383093(CHEMBL2031576)
Affinity DataIC50: 2.80nMAssay Description:Displacement of [125I]MCH from human MCHR1 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50383093(CHEMBL2031576)
Affinity DataIC50: 9.20nMAssay Description:Antagonist activity at human MCHR1 expressed in CHO cells assessed as inhibition of MCH-induced [3H]arachidonic acid release after 16 hrs by liquid s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50383093(CHEMBL2031576)
Affinity DataIC50: 160nMAssay Description:Displacement of [3H]mesulergine from human 5HT2C receptor expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed