BDBM50383371 CHEMBL2030550

SMILES CN1CCN(CC1)c1ccc(\C=C(/C#N)c2ccccc2Br)cc1

InChI Key InChIKey=ZJMDTBBCNMGFMS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50383371   

TargetPeroxisome proliferator-activated receptor delta(Human)
University of Oslo

Curated by ChEMBL
LigandPNGBDBM50383371(CHEMBL2030550)
Affinity DataIC50: 29nMAssay Description:Binding affinity to GST-PPAR-beta/delta LBP (unknown origin) after 40 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
University of Oslo

Curated by ChEMBL
LigandPNGBDBM50383371(CHEMBL2030550)
Affinity DataIC50: 30nMAssay Description:Binding affinity to GST-PPAR-beta/delta LBP (unknown origin) after 40 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Mouse)
Philipps University

Curated by ChEMBL
LigandPNGBDBM50383371(CHEMBL2030550)
Affinity DataIC50: 26.9nMAssay Description:Displacement of fluormone Pan-PPAR Green from mouse recombinant GST-tagged PPARbeta/delta LBD after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Mouse)
Philipps University

Curated by ChEMBL
LigandPNGBDBM50383371(CHEMBL2030550)
Affinity DataIC50: 9.5nMAssay Description:Inverse agonist activity at PPARbeta/delta in mouse C2C12 cells assessed as inhibition of Angptl4 expression after 24 hrs by RT-qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed