BDBM50383377 CHEMBL2030560::US10544104, Compound 92::US9765037, Compound 92

SMILES Nc1nc2ccc(cc2[nH]1)C(=O)c1ccccc1

InChI Key InChIKey=GPMHHSJZGVOEFS-UHFFFAOYSA-N

Data  2 KI  6 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50383377   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US9765037, Compound 92 | US1054410...)
Affinity DataIC50: 230nMAssay Description:Inhibition of Toxoplasma gondii CDPK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US9765037, Compound 92 | US1054410...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US9765037, Compound 92 | US1054410...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US9765037, Compound 92 | US1054410...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US9765037, Compound 92 | US1054410...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase ABL1(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US9765037, Compound 92 | US1054410...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent

TargetGastrotropin(Human)
Takeda Cambridge

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US9765037, Compound 92 | US1054410...)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to recombinant human N-terminal His6 and Avi-tagged FABP6 expressed in Escherichia coli NEB cells by surface plasmon resonance metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US9765037, Compound 92 | US1054410...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human SRC by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50383377(CHEMBL2030560 | US9765037, Compound 92 | US1054410...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human ABL by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed