BDBM50384527 CHEMBL2036422::US9073906, 5

SMILES O=C(CN1CCCN(Cc2ccccc2)S1(=O)=O)NC1C2CC3CC(C2)CC1C3

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50384527   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50384527(CHEMBL2036422 | US9073906, 5)
Affinity DataIC50: 360nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50384527(CHEMBL2036422 | US9073906, 5)
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro inhibitory activities of the novel compounds to human 11β-HSD1 were evaluated in accordance with homogenous time-resolved fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
Go to US Patent

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50384527(CHEMBL2036422 | US9073906, 5)
Affinity DataIC50: 360nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO-K1 cells using cortisone as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed