BDBM50384901 CHEMBL2036275

SMILES CCN[C@H]1CCC[C@H](C1)c1c[nH]c2ccc(cc12)N=C(N)c1cccs1

InChI Key InChIKey=RDNPSSHSVPTCKN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50384901   

TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50384901(CHEMBL2036275)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of human iNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50384901(CHEMBL2036275)
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50384901(CHEMBL2036275)
Affinity DataIC50: 1.63E+4nMAssay Description:Displacement of [3H]astemizole from human Erg expressed in HEK293 cells after 75 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50384901(CHEMBL2036275)
Affinity DataIC50: 730nMAssay Description:Inhibition of human nNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50384901(CHEMBL2036275)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human eNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed