BDBM50385474 CHEMBL2036748

SMILES CN1CCCC(CN2CCN(CC2)C(=O)Nc2ccc(Cl)c(Cl)c2)C1

InChI Key InChIKey=ZXBGDMYNCLFGDV-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50385474   

TargetC-C chemokine receptor type 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385474(CHEMBL2036748)
Affinity DataIC50: 170nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385474(CHEMBL2036748)
Affinity DataKi:  400nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human HEK cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385474(CHEMBL2036748)
Affinity DataIC50: 965nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50385474(CHEMBL2036748)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed