BDBM50385819 CHEMBL2043325

SMILES COc1cc(ncn1)N1C(=O)N(C(=O)C11CCN(Cc2ncccc2C)CC1)c1ccc(cc1)-c1ccc(cc1C)C(O)=O

InChI Key InChIKey=KAPZNJYOKZDXPF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50385819   

TargetProlyl hydroxylase EGLN3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385819(CHEMBL2043325)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PHD3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385819(CHEMBL2043325)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PHD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385819(CHEMBL2043325)
Affinity DataIC50: 1.30E+4nMAssay Description:Binding affinity to human ErgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385819(CHEMBL2043325)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385819(CHEMBL2043325)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385819(CHEMBL2043325)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385819(CHEMBL2043325)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed