BDBM50386292 CHEMBL2047851

SMILES N[C@H]1Cc2ccccc2N(O)C1=O

InChI Key InChIKey=HYTRYTZFJVVZAF-UHFFFAOYSA-N

Data  2 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50386292   

TargetKynurenine--oxoglutarate transaminase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataIC50: 9.04E+3nMAssay Description:Inhibition of human KAT3 using L-kynurenine as substrate measured after 24 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKynurenine--oxoglutarate transaminase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of human KAT1 using L-kynurenine as substrate measured after 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataIC50: 23nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate measured after 15-20 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataIC50: 263nMAssay Description:Inhibition of rat recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetKynurenine--oxoglutarate transaminase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human KAT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetKynurenine--oxoglutarate transaminase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human KAT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant KAT2 assessed as conversion of L-kynurenine into kynurenic acid after 15 to 20 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataIC50: 23nMAssay Description:Inhibition of Kynurenine aminotransferase II (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataKi:  14nMAssay Description:Irreversible inhibition of human KAT2 using L-kynurenine as substrate measured every 5 mins over 16 hrs by SpectraMax plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
LigandPNGBDBM50386292(CHEMBL2047851)
Affinity DataKi:  14nMAssay Description:Inhibition of human KAT2 using L-kynurenine as substrate after 15 to 20 hrs by UV-visible spectra analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed