BDBM50386475 CHEMBL2047879

SMILES Nc1ncnc2c(csc12)C(=O)Nc1c(Cl)ccc(NS(=O)(=O)CCCF)c1F

InChI Key InChIKey=DFIVZWWMRMZVLA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50386475   

TargetSerine/threonine-protein kinase B-raf(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50386475(CHEMBL2047879)
Affinity DataIC50: 22nMAssay Description:Inhibition of wild type B-raf in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50386475(CHEMBL2047879)
Affinity DataIC50: 73nMAssay Description:Inhibition of wild type C-raf in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50386475(CHEMBL2047879)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed