BDBM50386880 CHEMBL2048487

SMILES OC[C@H]1C[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cccc(Cc2ccc(cc2)C2CC2)c1

InChI Key InChIKey=ZXMWWEOFNKCIIA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50386880   

TargetSodium/glucose cotransporter 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50386880(CHEMBL2048487)
Affinity DataIC50: 11nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells by [14C]AMG uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50386880(CHEMBL2048487)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells by [14C]AMG uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50386880(CHEMBL2048487)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of CYP3A4 using BFC substrate in which compound added to reaction mixture before addition of BFC substrate by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50386880(CHEMBL2048487)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of CYP3A4 using BFC substrate in which compound added to reaction mixture simultaneously with BFC substrate by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed