BDBM50387294 CHEMBL2048869

SMILES CCOc1cccc(C=C2SC(O)=NC2=O)c1N1CCC[C@@H](N)C1

InChI Key InChIKey=YPGUAMCIYVJFOJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50387294   

TargetSerine/threonine-protein kinase pim-3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50387294(CHEMBL2048869)
Affinity DataIC50: 6nMAssay Description:Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50387294(CHEMBL2048869)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50387294(CHEMBL2048869)
Affinity DataIC50: 160nMAssay Description:Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387294(CHEMBL2048869)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed