BDBM50387525 CHEMBL2059906

SMILES O=C(N[C@H](Cc1csc2ccccc12)C(=O)N1CCC(CC1)N1CCCCC1)N1CCC2(CC1)NC(=O)Nc1ccccc21

InChI Key InChIKey=JQBAIBGWHDJVCY-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50387525   

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50387525(CHEMBL2059906)
Affinity DataEC50:  3nMAssay Description:Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated formation of cyclic AMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50387525(CHEMBL2059906)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]CGRP from CGRP receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50387525(CHEMBL2059906)
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50387525(CHEMBL2059906)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50387525(CHEMBL2059906)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50387525(CHEMBL2059906)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed