BDBM50387877 CHEMBL2057795

SMILES CCN1CCN(CC1)c1nc(C)nc2sc(cc12)-c1ccccc1

InChI Key InChIKey=CWQYMWNABHHDQG-UHFFFAOYSA-N

Data  2 KI  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50387877   

TargetCannabinoid receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50387877(CHEMBL2057795)
Affinity DataEC50:  24.8nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as [35S]-GTPgammaS binding preincubated for 25 mins measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50387877(CHEMBL2057795)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cells assessed as [35S]-GTPgammaS binding preincubated for 25 mins measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387877(CHEMBL2057795)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human Erg expressed in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50387877(CHEMBL2057795)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50387877(CHEMBL2057795)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CB1 receptor in rat cerebellar homogenates assessed as inhibition of CP-55,940-stimulated [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50387877(CHEMBL2057795)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at CB1 receptor in rat cerebellar homogenates assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50387877(CHEMBL2057795)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-CP-55,940 from rat CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50387877(CHEMBL2057795)
Affinity DataKi:  82nMAssay Description:Displacement of [3H]-CP-55,940 from human CB2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed