BDBM50388393 CHEMBL2058266

SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@]45O[C@@H]4CCC[C@]35C)[C@@H]1CCC2=O

InChI Key InChIKey=RHKHISPXHVJNPF-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50388393   

TargetAromatase(Human)
Univ Coimbra.

Curated by ChEMBL
LigandPNGBDBM50388393(CHEMBL2058266)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of aromatase in human MCF-7aro cells using [1beta-3H] androstenedione as substrate incubated for 1 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAromatase(Human)
Univ Coimbra.

Curated by ChEMBL
LigandPNGBDBM50388393(CHEMBL2058266)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of aromatase in disrupted human MCF-7aro cells using [1beta-3H] androstenedione as substrate incubated for 1 hrs in the presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAromatase(Human)
Univ Coimbra.

Curated by ChEMBL
LigandPNGBDBM50388393(CHEMBL2058266)
Affinity DataIC50: 970nMAssay Description:Inhibition of aromatase in human placental microsomes using [1beta-3H]androstenedione as substrate after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAromatase(Human)
Univ Coimbra.

Curated by ChEMBL
LigandPNGBDBM50388393(CHEMBL2058266)
Affinity DataKi:  86nMAssay Description:Inhibition of aromatase in human microsomes using [1beta-3H]androstenedione as substrate after 5 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed