BDBM50388688 CHEMBL550064

SMILES [H][C@@]12CC[C@]([H])(CC(C1)NC(=O)c1nn(C(C)C)c3ccccc13)N2

InChI Key InChIKey=PVLJAKPVNWWVDA-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50388688   

Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50388688(CHEMBL550064)
Affinity DataEC50:  39.8nMAssay Description:Agonist activity at human 5HT4C receptor expressed in HEK293 cells assessed as accumulation of cAMP by flash plate adenylyl cyclase activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50388688(CHEMBL550064)
Affinity DataKi:  63.1nMAssay Description:Displacement of [H]GR-113808 from human 5HT4C receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Theravance

Curated by ChEMBL
LigandPNGBDBM50388688(CHEMBL550064)
Affinity DataKi:  63.1nMAssay Description:Displacement of [3H]GR113808 from human recombinant 5HT4C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed