BDBM50388954 CHEMBL2063559

SMILES Fc1ccc2\C(=C\c3ccc(cc3)-c3ccccc3)C=C(CC(=O)NS(=O)(=O)C(F)(F)F)c2c1

InChI Key InChIKey=OESHADCPCVOHHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50388954   

TargetProstaglandin G/H synthase 1(Human)
Vanderbilt Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50388954(CHEMBL2063559)
Affinity DataIC50: 470nMAssay Description:Inhibition of ovine COX-1 using [14C] arachidonic acid as substrate preincubated for 17 mins before substrate addition measured after 3 mins by thin-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Vanderbilt Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50388954(CHEMBL2063559)
Affinity DataIC50: 495nMAssay Description:Inhibition of COX-1 in human OVCAR3 cells using [14C] arachidonic acid as substrate preincubated for 30 mins before substrate addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed