BDBM50389078 CHEMBL2064539

SMILES COC[C@H]1COc2ccc(cc2O1)-c1nnc(SCc2ccc(cc2)-c2ccccc2C#N)o1

InChI Key InChIKey=BDRSCIWOUKYOAH-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50389078   

TargetGlycogen synthase kinase-3 beta(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 129nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PKCalpha by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PKCalpha by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform epsilon(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CK1epsilon by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant AurKA by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CDK5/p35 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CDK5/p35 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform epsilon(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CK1epsilon by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant AurKA by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 233nMAssay Description:Inhibition of human recombinant GSK3beta using pIRS-1 as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50389078(CHEMBL2064539)
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant GSK3alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed