BDBM50389199 CHEMBL2062794

SMILES COc1ccccc1-c1cccn2nc(Nc3ccccc3)nc12

InChI Key InChIKey=HBCGXHDDFKAZGS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50389199   

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50389199(CHEMBL2062794)
Affinity DataIC50: 136nMAssay Description:Inhibition of human JAK2 expressed in baculovirus using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50389199(CHEMBL2062794)
Affinity DataIC50: 834nMAssay Description:Inhibition of human JAK3 expressed in baculovirus using biotinyl-amino-hexanoyl-EQEDEPEGDYFEWLE-amide as substrate preincubated for 1 hr measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed