BDBM50389752 CHEMBL2070096

SMILES CN(Cc1ccccc1)C(=O)c1sc(nc1C(F)(F)F)-c1ccc(c(c1)[N+]([O-])=O)S(C)(=O)=O

InChI Key InChIKey=OAFVIBMMYOJKFW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50389752   

TargetThyroid hormone receptor alpha(Human)
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50389752(CHEMBL2070096)
Affinity DataIC50: 460nMAssay Description:Antagonist activity at human TRalpha assessed as inhibition of interaction with SRC2-2 by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50389752(CHEMBL2070096)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at human TRbeta assessed as inhibition of interaction with SRC2-2 after 3 hrs by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Institut Pasteur Korea

Curated by ChEMBL
LigandPNGBDBM50389752(CHEMBL2070096)
Affinity DataIC50: 6.00E+4nMAssay Description:Antagonist activity at human PPAR-gamma assessed as inhibition of interaction with DRIP-2 by fluorescence polarisation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed