BDBM50389782 CHEMBL2070374

SMILES CCCC[C@H](NC(=O)[C@H](CNC(=O)CN(CC(O)=O)CC(O)=O)NC(=O)[C@H](CC1=CN=CN1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)COCCOCCNC(=O)CCCCCCCCCCCCCCCC1=NN=NN1)C(=O)N[C@H]1CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC2=CNC3=C2C=CC=C3)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@@H]2C[C@@H](O)CN2C1=O)C(N)=O

InChI Key InChIKey=BGQGGVJRXUWNNU-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50389782   

TargetMelanocortin receptor 4(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389782(CHEMBL2070374)
Affinity DataEC50:  88nMAssay Description:Agonist activity at human recombinant MC4 receptor expressed in BHK570 cells assessed as induction of cMAP accumulation in presence of 0.1% human ser...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389782(CHEMBL2070374)
Affinity DataKi:  0.580nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from MC4 receptor after 2 hrs by gamma counting in presence of ovalbuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389782(CHEMBL2070374)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC3 receptor human MC5 expressed in BHK570 cells after 1 hr in presence of ovalbuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389782(CHEMBL2070374)
Affinity DataKi:  71nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC3 receptor expressed in BHK570 cells after 1 hr in presence of ovalbuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50389782(CHEMBL2070374)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [125I]-NAD-alpha-MSH from human recombinant MC1 receptor expressed in BHK570 cells after 90 mins in presence of ovalbuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed