BDBM50389901 CHEMBL2070884

SMILES Cn1cc2c(n1)nc(NC(=O)NC1CCN(CC#C)CC1)n1nc(nc21)-c1ccco1

InChI Key InChIKey=OLHZYTQXINHKKZ-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50389901   

TargetAdenosine receptor A2b(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50389901(CHEMBL2070884)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of NECA-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50389901(CHEMBL2070884)
Affinity DataIC50: 105nMAssay Description:Antagonist activity at human adenosine A3 receptor expressed in CHO cells assessed as forskolin/C1-IB-MECA-induced inhibition of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50389901(CHEMBL2070884)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]MRE-3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50389901(CHEMBL2070884)
Affinity DataKi:  789nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in CHO cells after 60 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50389901(CHEMBL2070884)
Affinity DataKi:  802nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 120 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed