BDBM50390489 CHEMBL2071602

SMILES CN(C)c1ccc(\C=C\c2ccc3ncnc(NCc4ccccc4)c3c2)cc1

InChI Key InChIKey=KPIQHODXSDMYLR-UHFFFAOYSA-N

Data  1 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390489   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50390489(CHEMBL2071602)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to full-lenght/His-tagged ERBB2 UV-vis emission spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Miami

Curated by ChEMBL
LigandPNGBDBM50390489(CHEMBL2071602)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of ERBB2 autophosphorylation Thr 1139 residue in human BT474 cells at 2 to 14 uM after 12 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed