BDBM50391014 CHEMBL2088379

SMILES CCc1ccc(cc1)S(=O)(=O)C[C@@H]1C[C@@H](CC[C@@H]1NC(=O)Cc1nc2cccc(c2[nH]1)C(F)(F)F)N(C)C(C)C

InChI Key InChIKey=WYIDDZWJJNBWTK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391014   

TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50391014(CHEMBL2088379)
Affinity DataIC50: 2.80nMAssay Description:Binding affinity to CCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50391014(CHEMBL2088379)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at CCR2 in human monocytes by chemotaxis assay in presence of 0.5% bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed