BDBM50391711 CHEMBL2146958

SMILES Oc1ccc(\C=c2/sc3nc4ccccc4n3c2=O)cc1O

InChI Key InChIKey=PZIZLKJGPGUSCJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50391711   

TargetProtein-tyrosine-phosphatase(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50391711(CHEMBL2146958)
Affinity DataIC50: 900nMAssay Description:Inhibition of His-tagged PTPsigma catalytic domain amino acid 1369 to 1948 using DiFMUP as substrate after 20 mins by spectrofluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50391711(CHEMBL2146958)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of PRL1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 4(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50391711(CHEMBL2146958)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MKP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50391711(CHEMBL2146958)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of PRL3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50391711(CHEMBL2146958)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCo-chaperonin GroES(Escherichia coli)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50391711(CHEMBL2146958)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Escherichia coli GroEL/GroES expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed