BDBM50391799 CHEMBL2146897

SMILES OC1(CN2CCOCC2)CN(C1)C(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F

InChI Key InChIKey=RWVYUXIOUYZPHM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391799   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
TBA

Curated by ChEMBL

LigandBDBM50391799(CHEMBL2146897)Copy SMILESCopy InChI

Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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