BDBM50392358 CHEMBL2151487

SMILES Cc1cccc(c1)-c1noc(n1)C1CN(C1)C(=O)C1CCC(CC1)C(F)(F)F

InChI Key InChIKey=PEMKAJXXEDDMBX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392358   

TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50392358(CHEMBL2151487)
Affinity DataEC50:  1.00E+3nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in recombinant HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50392358(CHEMBL2151487)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in recombinant HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed