BDBM50392393 CHEMBL2151634

SMILES Cc1cccc(c1)-c1noc(n1)[C@@H]1CCN1C(=O)c1ccc(cc1)C#N

InChI Key InChIKey=KISVEYIIDMTDBM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392393   

TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50392393(CHEMBL2151634)
Affinity DataIC50: 1.40E+3nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in recombinant HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50392393(CHEMBL2151634)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in recombinant HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed