BDBM50392452 CHEMBL2151922

SMILES COc1cccc(NC(=O)Cc2nc(cc(=O)[nH]2)N2CCOCC2)c1

InChI Key InChIKey=RUVSRIAGPJOKFO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50392452   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Sanofi

US Patent
LigandPNGBDBM50392452(CHEMBL2151922)
Affinity DataIC50: 850nMT: 2°CAssay Description:This test is based on measuring the expression of the AKT protein phosphorylated on serine 473. The phosphorylation of AKT (pAKT) is measured by west...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details
Go to US Patent

LigandPNGBDBM50392452(CHEMBL2151922)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50392452(CHEMBL2151922)
Affinity DataIC50: 15nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50392452(CHEMBL2151922)
Affinity DataIC50: 611nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50392452(CHEMBL2151922)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50392452(CHEMBL2151922)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed