BDBM50392466 CHEMBL2151935
SMILES Cn1c(CC(=O)Nc2ccc(F)c(Cl)c2)nc(cc1=O)N1CCOCC1
InChI Key InChIKey=GGNJJMKBSUZZTH-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50392466
Affinity DataIC50: 202nMT: 2°CAssay Description:This test is based on measuring the expression of the AKT protein phosphorylated on serine 473. The phosphorylation of AKT (pAKT) is measured by west...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:This test is based on measuring the expression of the AKT protein phosphorylated on serine 473 (P-AKT-S473), in the PC3 human prostate carcinoma line...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Sanofi
Curated by ChEMBL
Sanofi
Curated by ChEMBL
Affinity DataIC50: 8.28E+3nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair