BDBM50392592 CHEMBL2153381

SMILES CCN(CC)CC(=O)NS(=C)(=O)c1ccc(cc1)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1

InChI Key InChIKey=JTKRQOZGONEGHX-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50392592   

TargetCoagulation factor X(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human F10a using S-2765 as substrate after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataKi:  1.10nMAssay Description:Inhibition of F10a assessed as S-2765 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProthrombin(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of thrombin assessed as S-2238 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPlasminogen(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of plasmin assessed as S-2302 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of tPA assessed as S-2288 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50392592(CHEMBL2153381)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of activated protein C assessed as S-2366 substrate hydrolysis by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed