BDBM50393998 CHEMBL2158440

SMILES Clc1ccc(Cl)c(CNc2nc(cc(=O)[nH]2)N2CCOCC2)c1

InChI Key InChIKey=UBWLDIYHFNNEKV-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50393998   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50393998(CHEMBL2158440)Copy SMILESCopy InChI

Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of human recombinant His6-tagged PI3K p110alpha expressed in baculovirus using DiC8-PI(4,5)P2 as substrate after 20 mins by AlphaScreen as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50393998(CHEMBL2158440)Copy SMILESCopy InChI

Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant His6-tagged PI3K p110beta expressed in baculovirus using DiC8-PI(4,5)P2 as substrate after 20 mins by AlphaScreen ass...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL