BDBM50394210 CHEMBL2159053

SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc(Cl)cc1)C(=O)c1ccc(Cl)cc1O

InChI Key InChIKey=LCVXUFKGARHCPF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394210   

TargetVascular endothelial growth factor receptor 2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50394210(CHEMBL2159053)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of VEGFR2 using gastrin as substrate after 60 mins by immunofluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50394210(CHEMBL2159053)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant Aurora A kinase using PLK as substrate incubated for 15 mins prior to substrate addition measured after 60 mins by im...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50394210(CHEMBL2159053)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50394210(CHEMBL2159053)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed