BDBM50394424 CHEMBL2159071

SMILES CN(Cc1cccs1)C(=O)C1(CC1)c1ccc(C)cc1

InChI Key InChIKey=LDZFSHKFVOIAHF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50394424   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 280nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-(trifluoromethyl) coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed