BDBM50394430 CHEMBL2158890

SMILES CN(Cc1cccs1)C(=O)CC12CC3CC(CC(C3)C1)C2

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394430   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394430(CHEMBL2158890)
Affinity DataIC50: 308nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394430(CHEMBL2158890)
Affinity DataIC50: 150nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-(trifluoromethyl) coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed