BDBM50394621 CHEMBL2164605::US9169224, 26

SMILES COc1cc(Br)cc(CN2CCN(CC2)C(=O)Nc2ccccc2)c1O

InChI Key InChIKey=OTTYIWVAUNQAOB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50394621   

TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394621(CHEMBL2164605 | US9169224, 26)
Affinity DataIC50: 79nMpH: 9.0Assay Description:Assay Method 1: T84 frozen pellets (contents of 1-4x15 cm culture dishes) were homogenized in 300 mL of FAAH assay buffer (125 mM Tris, 1 mM EDTA, 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394621(CHEMBL2164605 | US9169224, 26)
Affinity DataIC50: 210nMpH: 9.0Assay Description:Assay Method 1: T84 frozen pellets (contents of 1-4x15 cm culture dishes) were homogenized in 300 mL of FAAH assay buffer (125 mM Tris, 1 mM EDTA, 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394621(CHEMBL2164605 | US9169224, 26)
Affinity DataIC50: 130nMpH: 9.0Assay Description:T84 frozen cell pellets or transfected SK-N-MC cells (contents of 1x15 cm culture dishes) were homogenized in 50 mL of FAAH assay buffer (125 mM Tris...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
Go to US Patent

LigandPNGBDBM50394621(CHEMBL2164605 | US9169224, 26)
Affinity DataIC50: 243nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394621(CHEMBL2164605 | US9169224, 26)
Affinity DataIC50: 120nMAssay Description:Inhibition of human FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed