BDBM50394738 CHEMBL2165828

SMILES N=C(Nc1ccc2N(CCCc2c1)C1CCNC1)c1cccs1

InChI Key InChIKey=ARRHYORTUJNWLD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50394738   

TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394738(CHEMBL2165828)
Affinity DataIC50: 248nMAssay Description:Inhibition of human nNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394738(CHEMBL2165828)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of human eNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50394738(CHEMBL2165828)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells at -80 mV holding potential assessed as reduction in tail current amplitude by conventional patch c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed