BDBM50394743 CHEMBL2165820

SMILES CNCCN1CCCc2cc(NC(=N)c3cccs3)ccc12

InChI Key InChIKey=OGZIQVTYHMBLMX-UHFFFAOYSA-N

Data  3 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50394743   

TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394743(CHEMBL2165820)
Affinity DataIC50: 176nMAssay Description:Inhibition of human nNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50394743(CHEMBL2165820)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells at -80 mV holding potential assessed as reduction in tail current amplitude by conventional patch c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394743(CHEMBL2165820)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of human muscarinic M1 receptor by cell based functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394743(CHEMBL2165820)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of human muscarinic M4 receptor by cell based functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394743(CHEMBL2165820)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of human muscarinic M2 receptor by cell based functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394743(CHEMBL2165820)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of human muscarinic M3 receptor by cell based functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394743(CHEMBL2165820)
Affinity DataIC50: 4.07E+4nMAssay Description:Inhibition of human eNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated for 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50394743(CHEMBL2165820)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant iNOS expressed in Sf9 cells assessed as reduction in conversion of [3H]L-arginine to [3H]L-citrulline preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed