BDBM50394809 CHEMBL2163823

SMILES NC1CCN(CC1)C(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)C1(CC1)c1ccc(Cl)cc1Cl

InChI Key InChIKey=VNJOULOPKZCEMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394809   

TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394809(CHEMBL2163823)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human CYP3A4 using testosterone as substrate after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50394809(CHEMBL2163823)
Affinity DataIC50: 3nMAssay Description:Inhibition of GCS assessed as amount of UDP glucose after 3 hrs by Fluorometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed