BDBM50394912 CHEMBL2165510

SMILES Cn1ccc2c(cccc12)-c1nc(N2CCOCC2)c2sc(CN3CCN(CC3)C(C)(C)C(N)=O)cc2n1

InChI Key InChIKey=XZQRCJXLCKQEIT-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394912   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50394912(CHEMBL2165510)Copy SMILESCopy InChI

Affinity DataIC50: 134nMAssay Description:Binding affinity to PI3Kdelta after 30 mins by competitive fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetCytochrome P450 3A4(Human)
Genentech

Curated by ChEMBL

LigandBDBM50394912(CHEMBL2165510)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Time dependent inhibition of CYP3A4 in human liver microsomes preincubated for 30 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL