BDBM50395357 CHEMBL2164047

SMILES Fc1ccc(CCN2C(C(=O)NCc3ccc(OC(F)(F)F)cc3)c3ccccc3C2=O)nc1

InChI Key InChIKey=BTTKDIOGEICZEV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50395357   

LigandPNGBDBM50395357(CHEMBL2164047)
Affinity DataIC50: 5.30E+3nMAssay Description:Binding affinity to human ERG expressed in CHOK1 cells by IonWorks HT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395357(CHEMBL2164047)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395357(CHEMBL2164047)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human NaV1.5 alpha subunit expressed in CHOK1 cells at -90 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed