BDBM50395556 CHEMBL2165125

SMILES Clc1cccc(C2CCN(CCCCOc3ccc4CCC(=O)Nc4c3)CC2)c1Cl

InChI Key InChIKey=GHSXGIFSVHMKHZ-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50395556   

TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50395556(CHEMBL2165125)
Affinity DataEC50:  2nMAssay Description:Agonist activity at D2L receptor in human HTLA cells assessed as beta arrestin recruitment at 6 uM after 18 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50395556(CHEMBL2165125)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]N-methylspiperone from human D2L receptor expressed in CHO cells after 1.5 hrs by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50395556(CHEMBL2165125)
Affinity DataEC50:  363nMAssay Description:Agonist activity at human D2L receptor expressed in HEK293T cells coexpressing Gi subunit assessed as inhibition of isoproterenol-stimulated cAMP pro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed