BDBM50396234 CHEMBL2172214::US9402842, 57

SMILES CC(=O)Nc1ccc2c3C(=O)c4ccccc4-c3n(CCCN)c(=O)c2c1

InChI Key InChIKey=OAMSLKFEKYILAD-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50396234   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM50396234(CHEMBL2172214 | US9402842, 57)
Affinity DataIC50: 1.80E+4nMpH: 7.5 T: 2°CAssay Description:A 5′-[32P]-labeled single-stranded DNA oligonucleotide containing a 3′-phosphotyrosine (N14Y) was generated as described by Dexheimer et ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetRetinoic acid receptor RXR-alpha(Human)
The University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50396234(CHEMBL2172214 | US9402842, 57)
Affinity DataEC50: >4.14E+4nMAssay Description:Agonist activity at human RXRalpha expressed in african green monkey COS1 cells assessed as induction of RXRE transcriptional activity after 12 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue Research Foundation

US Patent
LigandPNGBDBM50396234(CHEMBL2172214 | US9402842, 57)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
The University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50396234(CHEMBL2172214 | US9402842, 57)
Affinity DataEC50: >3.47E+4nMAssay Description:Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed